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Friday 1 March 2013


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Tamoxifen citrate has a molecular weight of 563.62, the pKa' is 8.85, the equilibrium solubility in water at 37°C is 0.5 mg/mL and in 0.02 N HCl at 37°C, it is 0.2 ...
The breast cancer treatment drug tamoxifen has been widely administered for more than three decades. This small molecule competes with 17beta-estradiol for ...

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Jan 22, 2011 ... BACKGROUND: Aromatase inhibitors improved disease-free survival compared with tamoxifen when given as an initial adjuvant treatment or ...

Drs. Horn and Hansten are both profes- sors of pharmacy at the University of. Washington School of Pharmacy. For an electronic version of this article, including ...

Jan 24, 2011 ... Tamoxifen, the medication long used to prevent the growth of breast cancer tumors, also appears to reduce the risk of dying from lung cancer, ...

ABSTRACT: Tamoxifen may be associated with endometrial proliferation, hyperplasia, polyp formation, invasive carcinoma, and uterine sarcoma. Any symptoms ...

Tamoxifen citrate is also being studied in the treatment of other types of cancer. It blocks the effects of the hormone estrogen in the breast. Tamoxifen citrate is a ...

Background: Concerns have been raised that tamoxifen may be associated with depression. To investigate this question, we examined the psychological effects ...

Tamoxifen is a SERM, a PKC inhibitor and an anti-angiogenetic factor. Tamoxifen i is metabolized to 4-hydroxytamoxifen (4-OHT) and endoxifen by CYP2D6 ...

Q: What can you tell me about Arimidex vs. tamoxifen? Should a person on tamoxifen switch to Arimidex? And is there any benefit to taking Arimidex after five ...

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